ACG's 2014 Annual Scientific Meeting Annual Scientific Meeting Monday through Wednesday, October 20 through 22, 2014 • Terrace Ballroom Join GI physicians from around the U.S. and the world for the ACG Annual Scientific Meeting. The meeting promises to deliver the latest clinical information on timely topics in gastroenterology. As an ACG member, you can attend the three-day Annual Meeting for free – there is no registration fee. Choose from 11 symposia, multiple networking events, and see the latest advances in technology and therapeutics from exhibitors from around the globe. Additional breakfast sessions, 17 in total, will be offered for a nominal fee. Register today! Be sure to visit poster presentations in the Exhibit Hall on Sunday, October 19th beginning at 3:30 pm, and enjoy the Exhibit Hall Opening Reception beginning at 5:15 pm on Sunday. Program Description Returning this year is the Endoscopy Video Forum, “Live from Philly! The 2nd Annual Endoscopy Video Forum.” The Forum will feature the best video presentations submitted from colleagues from across the U.S. and around the world. Submitted during ACG’s Call for Abstracts and peer-reviewed and selected for presentation, the cases will feature endoscopy techniques, challenging or unique cases, and cases in the area of GI endoscopy. During the session, the audience, along with the Moderators, will vote to select the best video of ACG 2014. The field of gastroenterology and hepatology continues to see advancements in multiple areas relating to diagnostic measures, therapeutic options and technology. In order to provide appropriate and top-quality patient care, the clinician is challenged to stay abreast of the changes and advancements affecting the management of many gastrointestinal and liver disease states. Throughout the three-day Annual Meeting, you will be exposed to updates in a variety of topics, including biologic therapy in IBD, hepatitis C, acute and chronic pancreatitis, IBS, colonoscopy, the refractory esophageal patient, case studies in IBD management, the inpatient hepatology consult, the human microbiome, and more. The Annual Scientific Meeting program is designed primarily for physicians in gastroenterology and hepatology, as well as physician assistants, nurse practitioners and other advanced practice healthcare professionals interested in the latest information on state-of-the-art treatment of these illnesses. Eleven scientific plenary symposia will allow attendees to hear lecture presentations from experts and to participate in interactive question and answer sessions with the faculty. In addition, 17 optional scientific breakfast sessions will be offered, where a smaller setting allows for heightened interaction with the speakers and greater audience involvement. Accreditation The American College of Gastroenterology is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. Many sessions will use expert panel discussions in debate and case-based formats. The American College of Gastroenterology designates this live activity for a maximum of 16.25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Download ACG 2014 slides to your Apple or Android smart device with eventScribe! 23 ANNUAL MEETING Follow along with the presenter when you download slides using the eventScribe app by CadmiumCD. The eventScribe app, native to Apple and Android devices including tablets, phones, and Kindle Fire, can be downloaded in advance and used onsite during the meeting. eventScribe lets you take notes next to each slide, highlight information and draw on each slide. Save your notes to reference after the meeting. annual scientific meeting slides will be available on course available on Look for this symbol to see if eventScribe slide downloads are available. For more information on ACG 2014 and to register, visit www.acgmeetings.gi.org. Annual Scientific Meeting Agenda – Monday, October 20 Monday, October 20, 2014 breakfast c: GI Disease in Transitioning Teenagers: Adults Aren't Big Kids 6:30 am – 6:00 pm 6:00 am  –  4:45 pm Registration (Broad Street Atrium) moderator: Sandeep K. Gupta, MD, FACG Cystic Fibrosis Drucy S. Borowitz, MD Discuss issues that carry over with patients as they transition into adult practice, including nutrition and liver disease. 6:30 am  –  7:45 am OPTIONAL Breakfast Sessions Cost is $60 per person/per session. Separate registration required. A USB containing all ACG 2014 Breakfast Sessions submissions will be provided to attendees registered for any Breakfast Session. See page 124 for registration information. IBD Judith R. Kelsen, MD breakfast a: Outline how patients with childhood-onset IBD are different from adultonset disease. moderator: Ryan Madanick, MD EoE Sandeep K. Gupta, MD, FACG GIs in the Digital Age: The Power of Social Media Describe issues faced by teenagers with GI disease including diet compliance, medication use and independent access to health-care. To Socialize or Not to Socialize: The Pros and Cons of Social Media Sites Ryan Madanick, MD breakfast d: A Explain the threats to professionalism that involvement in social media poses and how these threats can be minimized, and monitor and begin to manage your own digital footprint. Conditions moderator: Philip O. Katz, MD, FACG Reputation Management: How to Use Your Online Brand to Bring in New Patients Kenneth Brown, MD GERD and Barrett’s Philip O. Katz, MD, FACG Explain how social media can improve patient care and how your online brand can be used to bring in new patients. Formulate a cost-effective approach for the management of GERD and Barrett’s esophagus. Case Studies in Social Media: Dos and Don’ts David T. Rubin, MD, FACG Constipation Amy E. Foxx-Orenstein, DO, FACG Select a social media platform appropriate for personal and professional needs. breakfast b: Atypical Cost-effective Approach to Common GI Assess the need for diagnostic testing in patients with chronic constipation. Dyspepsia Brian E. Lacy, MD, PhD, FACG Colitides Identify a cost-effective approach for the treatment of dyspepsia. moderator: Darrell S. Pardi, MD, FACG breakfast e: Endoscopy 101: Esophageal and Anorectal Motility, and Hands-on Microscopic Colitis: What’s New in Diagnosis and Management Darrell S. Pardi, MD, FACG Identify current and new methods to detect and treat microscopic colitis. moderator: Felice Schnoll-Sussman, MD, FACG The Spectrum of Diverticular Disease: SCAD, SUDD Brennan M. R. Spiegel, MD, MSHS, FACG Esophageal Manometry Felice Schnoll-Sussman, MD, FACG Utilize diagnostic tools to define the spectrum of diverticular diseases. Interpret common esophageal motility problems, followed by a hands-on demonstration. Ischemic Colitis Lawrence J. Brandt, MD, MACG Anorectal Manometry Satish S. C. Rao, MD, PhD, FACG Summarize the pathophysiology and know the methods for diagnosing and treating ischemic colitis. Interpret common anorectal motility problems, followed by a hands-on demonstration. Following the didactic lectures, attendees will participate in a hands-on session taking place in the Hands-on Workshop Center from 7:50 am9:00 am. For more information on ACG 2014 and to register, visit www.acgmeetings.gi.org. 24 Annual Scientific Meeting Agenda – Monday, October 20 6:00 am  –  4:45 pm Registration (Broad Street Atrium) 7:50 am  –  6:00 pm Scientific Meeting 7:50 am  –  8:00 am Opening Remarks 8:00 am  –  9:00 am ModeratoRS: Paris Descartes et Hôpital, Paris, France, Hopital Saint Joseph, Marseille, France, Complejo Hospitalario Universitario A Coruña, A Coruña, Spain, Hospital Universitario La Fe, Valencia, Spain, AbbVie, Inc., North Chicago, IL (Terrace Ballroom) Harry E. Sarles, Jr., MD, FACG ACG President 9:00 am  –  9:30 am President’s Address (Terrace Ballroom) Harry E. Sarles, Jr., MD, FACG Introduced by: Stephen B. Hanauer, MD, FACG ACG President-Elect PRESIDENT'S Plenary Session 1 (Terrace Ballroom) Harry E. Sarles, Jr., MD, FACG John R. Saltzman, MD, FACG 9:30 am  –  10:30 am 1. Dronabinol Increases Pain Threshold in Non-Cardiac Chest Pain: A Double Blind Placebo Controlled Trial  2014 ACG Auxiliary Award (Trainee) Zubair Malik, MD, Levant Bayman, MSc, Jessica Valestine, BSc, Ron Schey, MD, Temple University Hospital, Philadelphia, PA, University of Iowa Hospitals and Clinics, Iowa City, IA ModeratoRS: PRESIDENT'S Plenary Session 2 (Terrace Ballroom) Stephen B. Hanauer, MD, FACG John R. Saltzman, MD, FACG 6. Capnographic Monitoring Does Not Improve Detection of Hypoxemia in Colonoscopy With Moderate Sedation. A Randomized, Controlled Trial  2014 ACG Fellow Award Paresh P. Mehta, MD, Gursimran Kochhar, MD, Mazen Albeldawi, MD, Brian Kirsh, MD, Maged K. Rizk, MD, Brian Putka, MD, Binu John, MD, Yinghong Wang, MD, Nicole Breslaw, MD, John J. Vargo, MD, FACG, Cleveland Clinic, Cleveland, OH 2. Metal Versus Plastic for Pancreatic Pseudocyst Drainage: Clinical Outcomes and Success Reem Z. Sharaiha, MD, MSc, Ersilia M. DeFilippis, MD, Prashant Keida, MD, Christine Boumitri, MD, Huei-Wen Lim, MD, Eugene Han, MD, Harkarit Singh, MD, Saad S. Ghumman, MD, Monica Gaidhane, MD, Thomas Kowalski, MD, David Loren, MD, Michel Kahaleh, MD, FACG, Ali Siddiqui, MD, Weill Cornell Medical Center, New York, NY, Thomas Jefferson University, Philadelphia, PA 7. Young-Onset Colorectal Cancer: A More Aggressive Disease on the Rise  2014 ACG Colorectal Cancer Prevention Award Xi E. Zheng, MD, PhD, Heather Yeo, MD, MHS, Doron Betel, PhD, Manish A. Shah, MD, Weill Cornell Medical College, New York, NY 3. Gender Differences in Research Productivity, Academic Rank and Career Duration Among U.S. Academic Gastroenterology Faculty  2014 ACG/Naomi Nakao Gender-Based Research Award Sarah J. Diamond, MD, Brintha K. Enestvedt, MD, MBA, Charles Thomas, MD, Sima Desai, MD, Reshma Jagsi, MD, Colleen Schmitt, MD, Oregon Health and Science University, Portland, OR, University of Michigan, Ann Arbor, MI, Galen Medical Group, Chattanooga, TN 8. Impact of Retroflexion Versus Second Forward View Examination of the Right Colon on Adenoma Detection: A Multicenter Randomized Controlled Trial  2014 ACG Colorectal Cancer Prevention Award Vladimir M. Kushnir, MD, Young Oh, MD, Thomas Hollander, BS, Chien-Huan Chen, MD, PhD, Gregory S. Sayuk, MD, MPH, Nicholas Davidson, MD, FACG, Daniel Mullady, MD, Faris M. Murad, MD, Noura M. Sharabash, MD, Eric Ruettgers, MSN, RN, ANP-BC, Themistocles Dassopoulos, MD, Jeffrey J. Easler, MD, C. Prakash Gyawali, MD, FACG, Steven A. Edmundowicz, MD, Dayna S. Early, MD, FACG, Washington University School of Medicine, St. Louis, MO, Medical College of Wisconsin, Milwaukee, WI 9. Colonoscopy Is Associated With a Reduced Risk of Colon Cancer and Mortality in Patients With Inflammatory Bowel Diseases  2014 ACG Auxiliary Award (Member/Fellow) Ashwin Ananthakrishnan, MD, MPH, Andrew Cagan, BS, Tianxi Cai, PhD, Vivian Gainer, MS, Stanley Shaw, MD, PhD, Susanne Churchill, PhD, Elizabeth Karlsin, MD, MPH, Shawn Murphy, MD, PhD, Isaac Kohane, MD, PhD, Katherine Liao, MD, MPH, Massachusetts General Hospital, Boston, MA, Brigham and Women’s Hospital, Boston, MA, Harvard School of Public Health, Boston, MA, Partners Healthcare, Boston, MA 5. Normalization of Liver-Related Laboratory Parameters in HCV Genotype 1-Infected Patients With Cirrhosis After Treatment With ABT-450/R/Ombitasvir, Dasabuvir and Ribavirin Gregory Everson, MD, Samuel Lee, MD, Stefan Zeuzem, MD, Pietro Andreone, MD, Stanislas Pol, MD, Marc Bourlière, MD, Angeles Castro, MD, PhD, Marina Berenguer, MD, Sandra Lovell, PhD, Marcos Pedrosa, MD, PhD, Roger Trinh, MD, MPH, University of Colorado Denver and Hospital, Aurora, CO, University of Calgary, Calgary, Alberta, Canada, J.W. Goethe University, Frankfurt, Germany, University of Bologna, Bologna, Italy, Université ANNUAL MEETING 4. SVR12 of 99% Achieved With a Ribavirin-Free Regiment of ABT-450/r/Ombitasvir and Dasabuvir in HCV Genotype 1bInfected Patients  2014 ACG International Award Andreas Maieron, MD, Massimo Puoti, MD, Jeffrey Enejosa, MD, Ziv Ben-Ari, MD, Gunnar Norkrans, MD, Manuel RomeroGomez, MD, Wangang Xie, MD, PhD, Daniel Cohen, MD, Thomas Podsadecki, MD, Pietro Andreone, MD, Elisabeth Hospital, Linz, Austria, A.O. Ospedale Niguarda Ca Granda, Milan, Italy, AbbVie, Inc., North Chicago, IL, The Chaim Sheba Medical Center, Tel Hashomer, Israel, Sahlgrenska University Hospital, Göteborg, Sweden, Hospital Universitario Nuestra Senora De Valme, Seville, Spain, University of Bologna, Bologna, Italy 10. The Effect of Immunosuppressive Therapy on Cardiovascular Disease in Patients With Inflammatory Bowel Disease Sudeep D. Thapa, MD, Hiba Hadid, MD, Syed-Mohammed Jafri, MD, Mohammed Imam, DO, Jason Schairer, MD, Internal Medicine, Henry Ford Hospital, Detroit, MI 25 For more information on ACG 2014 and to register, visit www.acgmeetings.gi.org. Annual Scientific Meeting Agenda – Monday, October 20 10:00 am  –  4:30 pm Exhibit Hall Opens 10:00 am  –  4:30 pm Hands-on Workshop Center Plenary Session 1: Functional Bowel Disorder/Pediatrics (Exhibit Halls DE) MODERATORS: Brian E. Lacy, MD, PhD, FACG 10:30 am  –  11:30 am Break – Visit Exhibits 10:30 am  –  11:30 am Exhibitor theater 11:30 am  –  12:45 pm Simultaneous Symposia 1 2:15 pm  –  3:00 pm Simultaneous Plenary Sessions (Exhibit Halls DE) Samra Sarigol-Blanchard, MD 11. Linaclotide Efficacy on Dyspepsia Symptoms Using Nepean Dyspepsia Index (NDI) in a Phase 3B Trial of CIC Patients With Bloating Anthony Lembo, MD, Nicholas J. Talley, MD, PhD, FACG, Steven J. Shiff, MD, Bernard J. Lavins, MD, Robyn T. Carson, MPH, Rick Blakesley, PhD, Xinming Hao, PhD, Mark G. Currie, PhD, Caroline Kurtz, PhD, Jeffrey M. Johnston, MD, University of Newcastle, Callaghan, New South Wales, Australia, Forest Laboratories, Jersey City, NJ, Ironwood Pharmaceuticals, Cambridge, MA (Exhibit Halls DE) (Exhibit Halls DE) simultaneous symposia 1a:Choosing Biologic Therapy for IBD and Monitoring moderator: David T. Rubin, MD, FACG 12. Analysis of Exhaled Volatile Organic Compounds Reveals New Biomarkers for Irritable Bowel Syndrome  2014 ACG Fellow Award Sophia A. Patel, MD, Nishaben Patel, MD, Vera Okwu, MD, Ammar Matloob, MD, David Grove, PhD, Ellen Rome, MD, Raed Dweik, MD, Naim Alkhouri, MD, Pediatric GI, Cleveland Clinic Children’s, Cleveland, OH; Cleveland Clinic Respiratory Institute, Cleveland, OH; Cleveland Clinic Pediatric Department, Cleveland, OH Positioning Biologics in Ulcerative Colitis Bruce E. Sands, MD, FACG Describe how timing and selection factor into the implementation of biologic therapy for UC. Positioning Biologics in Crohn’s Disease David T. Rubin, MD, FACG Describe how timing and selection factor into the implementation of biologic therapy for Crohn’s disease. 13. Urgency as a Measure of Treatment Effect Due to Eluxadoline Anthony Lembo, MD, David Andrae, MD, Scott Dove, MD, Paul Covington, MD, Beth Israel Deaconess Medical Center, Boston, MA, Furiex Pharmaceuticals, Morrisville, NC Appropriate Use and Interpretation of Drug Levels Marla C. Dubinsky, MD Incorporate a rational approach to therapeutic drug monitoring in IBD. Apply recent phase 3 treatment options for genotype 1 infected individuals who are treatment naïve and non-responders to previous therapy. 14. Plecanatide, a Novel Uroguanylin Analog: A 12-week, Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Trial to Evaluate Efficacy and Safety in Patients With Irritable Bowel Syndrome With Constipation (IBS-C) Philip B. Miner, MD, FACG, Robert DeLuca, MD, Marianela D. La Portilla, MD, Eveline Padila, MD, William Koltun, MD, Othon H. Wiltz, MD, Kunwar Shailubhai, PhD, MBA, Gary S. Jacob, PhD, Patrick Griffin, MD, Laura M. Barrow, PharmD, R&D, Synergy Pharmaceuticals, Inc., Doylestown, PA, Genoma Research Group, Miami, FL, Columbus Clinical Services, Miami, FL, Medical Center for Clinical Research, San Diego, CA, Oklahoma Center for Clinical Research, Oklahoma City, OK, Medical Research Unlimited, Hialeah, FL, South Medical Research Center, Miami, FL Genotype 2/3 Other Populations Andrew J. Muir, MD, MHS Plenary Session 2: IBD simultaneous symposia 1b: Hepatitis Arrived C: The Future Has moderator: Stanley M. Cohen, MD Evaluating Your Patient for Therapy Using All Oral Therapies Stanley M. Cohen, MD Use elastography to identify patients with hepatitis C (including fibrosis assessment). Genotype 1 Treatment Options Mitchell L. Shiffman, MD, FACG Apply treatment options for genotype 2/3 infected individuals including nonresponding genotype 3 cirrhotic patients, implement treatment strategies in special populations including those who are (a) HCV/HIV infected and (b) awaiting liver transplant, and explain post-transplant outcomes. 12:45 pm  –  1:30 pm Exhibitor Theater 12:45 pm  –  2:15 pm Lunch Break – vISIT EXHIBITS 12:45 pm  –  2:15 pm Poster Session 1:45 pm  –  2:15 pm exhibitor theater MODERATORS: Uma Mahadevan, MD, FACG Sunanda V. Kane, MD, MSPH, FACG 15. Infliximab or Cyclosporine as Rescue Therapy in Patients With Severe Ulcerative Colitis Refractory to Steroids: A Systematic Review and Meta-Analysis Neeraj Narula, MD, John K. Marshall, MD, Jean-Frederic Colombel, MD, PhD, Grigorios I. Leontiadis, MD, Zack Muqtadir, MD, Walter Reinisch, MD, PhD, Mount Sinai Hospital, New York, NY, McMaster University, Hamilton, Ontario, Canada (Exhibit Halls DE) (Exhibit Halls DE) (Exhibit Halls DE) (Exhibit Halls DE) For more information on ACG 2014 and to register, visit www.acgmeetings.gi.org. 26 Annual Scientific Meeting Agenda – Monday, October 20 16. Safety of Vedolizumab Alone or With Concomitant Corticosteroids and/or Immunosuppressants in Patients With Ulcerative Colitis or Crohn’s Disease Edward V. Loftus, MD, FACG, Jean-Frederic Colombel, MD, PhD, Corey A. Siegel, MD, James D. Lewis, MD, FACG, Brihad Abhyankar, MBA, Serap Sankoh, PhD, Michael Smyth, MBA, Catherine Milch, MD, Mayo Clinic, Rochester, MN, Icahn School of Medicine at Mount Sinai, New York, NY, Dartmouth-Hitchcock Medical Center, Lebanon, NH, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, Takeda Global Research and Development Centre (Europe) Ltd., London, U.K., Takeda Pharmaceuticals International Co., Cambridge, MA 4:45 pm  –  6:00 pm simultaneous symposia 2a:Clearing moderator: Santhi Swaroop Vege, MD, FACG Changing Outcomes in Acute Pancreatitis Santhi Swaroop Vege, MD, FACG Identify the management options in acute pancreatitis which improve patient outcomes. Painful Chronic Pancreatitis: Scope or Knife Timothy B. Gardner, MD, MS, FACG Differentiate between the endoscopic or surgical management of chronic pancreatitis. Evaluation and Management of Pancreatic Cysts William R. Brugge, MD, FACG Determine the most appropriate treatment and management strategies for pancreatic cysts. simultaneous symposia 2b:Deciphering IBS: Understanding the Diverse Pathophysiology moderator: William D. Chey, MD, FACG Food Allergies and Food Sensitivities in IBS Sheila E. Crowe, MD, FACG 18. Post-Operative Mortality for the Inflammatory Bowel Diseases: A Systematic Review and Meta-Analysis of Population-Based Studies  2014 ACG Fellow Award Sundeep Singh, MD, Ahmed Al-Darmaki, MD, Alexandra Frolkis, PhD, Cynthia H. Seow, MD, Yvette P. Leung, MD, Kerri L. Novak, MD, Subrata Ghosh, MD, Remo Panaccione, MD, Gilaad G. Kaplan, MD, Division of Gastroenterology, University of Calgary, Calgary, Alberta, Canada, Department of Medicine, University of Calgary, Calgary, Alberta, Canada Counsel IBS patients on how foods contribute to the generation of IBS symptoms. An Evidence-based Approach to Dietary Treatment of IBS Brian E. Lacy, MD, PhD, FACG Perform an evidence-based review of different diets used to treat IBS. IBS as an Inflammatory Condition William D. Chey, MD, FACG Identify new physiologic processes involved in the development of IBS and discuss potential treatments. he American Journal of T Gastroenterology Lecture simultaneous symposia 2c:Live from Philly! The 2nd Annual Endoscopy Video Forum (Terrace Ballroom 3) Treatment of IBD: Where We Are and Where We Are Going Charles N. Bernstein, MD, FACG Evaluate the latest treatment options for patients with IBD. moderators: Seth A. Gross, MD, FACG, David A. Greenwald, MD, FACG, and Daniel J. Pambianco, MD, FACG Exhibitor theater 3:45 pm  –  4:40 pm Break – Visit Exhibits 3:55 pm  –  4:35 pm ABIM’s Maintenance of Certification Program (Room 122AB) Attend this informational session to understand how the changes to ABIM’s MOC Program requirements affect you. (Exhibit Halls DE) (Exhibit Halls DE) ANNUAL MEETING This Video Forum Symposium will feature the best video presentations submitted by colleagues from across the U.S. and around the world. Submitted during ACG’s Call for Abstracts and peer-reviewed and selected for presentation, the cases will feature endoscopy techniques, challenging or unique cases, and cases in the area of GI endoscopy. During the session, the audience, along with the Moderators, will vote to select the best video of ACG 2014. Attendees will view videos showcasing interesting endoscopic findings and techniques encountered in daily clinical practice. See page 4 for more information. 3:30 pm  –  4:30 pm Up Confusion in Day-to-day Pancreatic Issues 17. Does End-to-End Versus Side-to-Side Anastomosis in Postoperative Crohn’s Disease Matter? Prospective 2-Year Evaluation of Postoperative Quality of Life, Health Care Utilization, and Clinical Activity Mahesh Gajendran, MD, Claudia Ramos Rivers, MD, Jana G. Hashash, MD, Miguel D. Regueiro, MD, FACG, Andrew Watson, MD, Anthony J. Bauer, PhD, Leonard Baidoo, MD, Arthur M. Barrie, MD, Marc Schwartz, MD, Jason Swoger, MD, MPH, Michael A. Dunn, MD, David G. Binion, MD, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh, Pittsburgh, PA, Division of Colorectal Surgery, University of Pittsburgh, Pittsburgh, PA 3:00 pm  –  3:45 pm Simultaneous Symposia 2 V1. Incarcerated, Retroflexed Endoscope Associated With a Para-Esophageal Hernia Yazen Qumsiyeh, BS, Bashar Qumseya, MD, MPH, Michael Wallace, MD, MPH, FACG, Herbert Wolfsen, MD, FACG, Mayo Clinic Florida, Jacksonville, FL 27 For more information on ACG 2014 and to register, visit www.acgmeetings.gi.org. Annual Scientific Meeting Agenda – Tuesday, October 21 Tuesday, October 21, 2014 V2. Endoscopic Management of High-Grade Dysplastic Barrett’s With Esophageal Varices William Palmer, MD, Milena Di Leo, MD, Manol Jovani, MD, Herbert Wolfsen, MD, FACG, Murli Krishna, MD, Michael Wallace, MD, MPH, FACG, Mayo Clinic, Jacksonville, FL, Vita-Salute San Raffaele University, Scientific Institute San Raffaele, Milan, Italy, Humanitas Research Hospital, Milan, Rozzano, Italy 6:45 am – 6:15 pm 6:00 am  –  5:00 pm 6:45 am  –  8:15 am OPTIONAL Breakfast Sessions Cost is $60 per person/per session. Separate registration required. A USB containing all ACG 2014 Breakfast Sessions submissions will be provided to attendees registered for any Breakfast Session. See page 124 for registration information. V3. Endoscopic Full Thickness Resection (EFTR) of a Subepithelial Tumor With Extensive Muscularis Propria (MP) Involvement Stavros Stavropoulos, MD, Rani Modayil, MD, John Allendorf, MD, Collin Brathwaite, MD, James Grendell, MD, Winthrop University Hospital, Mineola, New York, NY breakfast f: Doctor, Do I Have to Take this Medicine Forever? Escalation and De-escalation of Therapy in IBD V4. Percutaneous Endoscopic Debridement and Washout of a Bilateral, Loculated, Hepatic Abscess: A Minimally Invasive Approach to a High-Risk Surgical Situation Ryan Gaffney, DO, Niraj Gusani, MD, MS, Neil Bhayani, MD, MHS, Karen Krok, MD, Ian Schreibman, MD, Abraham Mathew, MD, MHES, Matthew Moyer, MD, MS, Penn State Milton S. Hershey Medical Center and College of Medicine, Hershey, PA Moderator: Miguel D. Regueiro, MD, FACG Can You Stop Therapy in the Patient in Deep Remission? Asher Kornbluth, MD Adjust therapy for patients’ deep remission. Approach to the Patient Not in Deep Remission: Treat to Target Jean-Paul Achkar, MD, FACG V5. Successful Endoscopic Resection of Stage T1 Intraductal Biliary Adenocarcinoma Truptesh Kothari, MD, MS, Christine Granato, MD, Shivangi Kothari, MD, Glen Hintz, MS, Jennifer Lewis, MD, Asad Ullah, MD, Ashok Shah, MD, Vivek Kaul, MD, FACG, University of Rochester Medical Center, Rochester, NY, G. Hintz, Rochester Institute of Technology, Rochester, NY Describe the concept of treat-to-target and its current application to practice. Continuing Therapy in the Patient With Infection or Malignancy Miguel D. Regueiro, MD, FACG Justify the use of biologics during a treatment complication and identify when to stop immunosuppression. V6. Endoscopic Therapy Using Self-Expandable Metal Stents for Walled-Off Pancreatic Necrosis Susana Lopes, MD, Filipe Vilas-Boas, MD, Pedro Pereira, MD, Armando Ribeiro, MD, Guilherme Macedo, MD, PhD, Centro Hospitalar S. João, Porto, Portugal breakfast g: Using Practice New ACG Guidelines in Clinical Moderator: John E. Pandolfino, MD, FACG Esophageal Eosinophilia and EoE: Are They Different? Evan S. Dellon, MD V7. Endoscopic Mucosal Resection of a Diverticular Polyp Raul Badillo, MD, Michael Wallace, MD, MPH, FACG, Mayo Clinic, Jacksonville, FL Describe the new ACG clinical guidelines for EoE and esophageal eosinophilia. V8. Endoscopic Retrograde Appendicitis Therapy (ERAT): A New Endoscopic Technique From China Jitao Song, MD, Bing-Rong Liu, MD, PhD, The Second Affiliated Hospital of Harbin Medical University, Harbin, China 6:00 pm  –  6:30 pm Registration (Broad Street Atrium) GERD: PPIs and Is There a Dark Side? Marcelo F. Vela, MD, MSCR, FACG Explain the new ACG clinical guidelines for GERD. Achalasia: Diagnosis and Optimization of Treatment John E. Pandolfino, MD, FACG Annual Business Meeting Discuss the new ACG clinical guidelines for achalasia. (Terrace Ballroom 3) College Members and Fellows invited. breakfast h: Common (Yet Controversial) Topics in Pancreaticobiliary Disease Moderator: Douglas G. Adler, MD, FACG SOD: Does it Exist? Martin L. Freeman, MD, FACG Explain the latest evidence characterizing sphincter of Oddi dysfunction. Gallbladder Polyps: What to Do? Jason D. Conway, MD Judge when to resect, when to follow and when to ignore. Large Stones Made Easy Douglas G. Adler, MD, FACG Discuss the techniques to be used alone and in combination to remove large stones. For more information on ACG 2014 and to register, visit www.acgmeetings.gi.org. 28 Annual Scientific Meeting Agenda – Tuesday, October 21 breakfast i: breakfast l: Functional Anorectal Disease: Do Ask Fatty Liver Diseases: You Can’t Escape and Do Tell Them Moderator: Amy E. Foxx-Orenstein, DO, FACG Moderator: Mary E. Rinella, MD, FACG Urgency, Tenesmus and Leakage: How Can I Help? Satish S. C. Rao, MD, PhD, FACG Non-Alcoholic Fatty Liver Disease: What Is Beyond Vitamin E? Mary E. Rinella, MD, FACG Evaluate patients with non-alcoholic fatty liver disease and identify which patients require a liver biopsy and which can be followed. Discuss current therapies available and those in the pipeline. Explain the physiology of the pelvic floor and identify risk factors for tenesmus, urgency and fecal soiling. Medical, Endoscopic and Surgical Treatments for Incontinence Michael D. Brown, MD, FACG One Bourbon, One Scotch and One Beer: What to Do When They Are Drinking Vijay H. Shah, MD, FACG Discuss evidence-based therapies for the treatment of fecal incontinence. Pelvic Floor Dysfunction: How to Diagnose and How to Treat Amy E. Foxx-Orenstein, DO, FACG Classify clinical spectrum of alcoholic fatty liver disease, who requires therapy and with what, and how to apply the Lille criteria in treatment of alcoholic hepatitis. Identify the patient with pelvic floor dysfunction and construct an individualized treatment program. Recognizing and Preventing Drug-induced Liver Injury in Those With Chronic Liver Disease, Including Those With Fatty Liver Victor J. Navarro, MD breakfast j: Pushing the Envelope With New Endoscopic Techniques Discuss the latest techniques and devices for closing luminal perforations. Identify the different types of drug-induced liver disease, explain how those with non-alcoholic fatty liver disease, in general, are not at higher risk of drug-induced liver injury, determine how much acetaminophen can be administered and which populations require caution, and plan how to approach patients with chronic liver disease who require potentially hepatotoxic medicines. Want to Lose Weight? The Endoscopic Options Richard I. Rothstein, MD, FACG breakfast m: Medicolegal Moderator: Richard I. Rothstein, MD, FACG Perforation: We Can Fix That! Louis-Michel Wong Kee Song, MD Describe endoscopic management of obesity. Issues in Gastroenterology Moderator: Richard S. Bloomfeld, MD, FACG Endoscopic Treatment of Hemorrhoids Waqar A. Qureshi, MD, FACG Why Are Gastroenterologists Sued? Richard S. Bloomfeld, MD, FACG Identify new endoscopic therapies for hemorrhoid treatment. Identify top reasons gastroenterologists are named in lawsuits. Documentation and Communication Tips to Prevent Lawsuits John Baillie, MB, ChB, FACG breakfast k: The Gastroenterologist and the Pregnant Patient Moderator: Sunanda V. Kane, MD, MSPH, FACG Describe ways to improve documentation and communication to modify your risk of adverse medicolegal events. GI Meds in Pregnancy Sunanda V. Kane, MD, MSPH, FACG Refusing and Dismissing Problem Patients Andrew D. Feld, MD, JD, FACG Identify available pharmacological therapies that are safe for treatment of GI disorders in the pregnant patient. Establish policies for handling challenging patients in your practice. IBD and Pregnancy Sonia Friedman, MD, FACG 6:00 am  –  5:00 pm Registration (Broad Street Atrium) 8:30 am  –  6:15 pm Scientific Meeting 8:30 am  –  10:00 am SIMULTANEOUS Plenary SessionS Define strategies for a successful pregnancy outcome in the IBD patient, including fertility, preparation of the patient for pregnancy, monitoring and postpartum issues. Plenary Session 1:  Endoscopy / Colorectal Cancer Prevention MODERATORS: Mark B. Pochapin, MD, FACG Evaluate diagnostic and management options for liver diseases in pregnancy. David A. Johnson, MD, MACG 19. A Phase IIb Study Comparing the Safety and Efficacy of Remimazolam and Midazolam in Colonoscopy Patients Daniel J. Pambianco, MD, FACG, Keith Borkett, BSc, Dennis Riff, MD, Peter Winkle, MD, Howard Schwartz, MD, Timothy Melson, MD, Karin Wilhelm-Ogunbiyi, MD, Charlottesville Medical Research, Charlottesville, VA, Paion UK Ltd., Cambridge, United Kingdom, Anaheim Clinical Trials, Anaheim, CA, Miami Research Institute, Miami, FL, Helen Keller Hospital, Sheffield, AL, PAION Deutschland GmbH, Anchen, Germany 29 ANNUAL MEETING Liver Disease in Pregnancy Tram T. Tran, MD For more information on ACG 2014 and to register, visit www.acgmeetings.gi.org. Annual Scientific Meeting Agenda – Tuesday, October 21 20. What Is the Optimum Time to Do Endoscopy in Acute Caustic Ingestion? Munish Ashat, MD, Pradeep K. Siddappa, DM, Saroj K. Sinha, DM, Usha Dutta, DM, Rakesh Kochhar, DM, Gastroenterology, Post Graduate Institute of Medical Education and Research, Panchkula, Haryana, India sity School of Medicine, New Orleans, LA; Louisiana Tumor Registry, School of Public Health, Louisiana State University Health Sciences Center, New Orleans, LA 27B. Population-Based Lynch Syndrome (LS) Screening in Colorectal Cancer (CRC) Patients Aged ≤50 Years: A Statewide Analysis of Timing of Microsatellite Instability (MSI) Test Result Availability in Relation to Surgery  2014 ACG Governors Award for Excellence in Clinical Research Jordan J. Karlitz, MD, Mei-chin Hsieh, MSPH, Yong Liu, BS, Christine Blanton, MD, Beth Schmidt, MD, Meredith Sherrill, MD, Sanjay Sikka, MD, Giuseppe Gagliardi, MD, Xiao-Cheng Wu, MD, MPH, Vivien W. Chen, PhD, MD, Medicine, Tulane University School of Medicine, New Orleans, LA, Louisiana Tumor Registry, School of Public Health, Louisiana State University Health Sciences Center, New Orleans, LA 21. Volumetric Laser Endomicroscopy in Barrett’s Esophagus – Feasibility of Use and Detection of Dysplasia in Clinical Practice Jeffrey Mosko, MD, FRCPC, Sumeet K. Tewani, MD, Ivana Dzeletovic, MD, Gyanprakash Ketwaroo, MD, Tyler Berzin, MD, Ram Chuttani, MD, Mandeep Sawhney, MD, Douglas Pleskow, MD, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 22. Natural Orifice Endoscopic Surgery (NOTES) Techniques for Full Thickness R0 Endoscopic Resection of Deep Seated Subepithelial Tumors (SETs): First U.S. Cases Stavros Stavropoulos, MD, Rani J. Modayil, MD, Collin Brathwaite, MD, Kumkum S. Patel, MD, Thomas Coppola, DO, John Allendorf, MD, David Friedel, MD, James Grendell, MD, Winthrop University Hospital, Mineola, NY Plenary Session 2: Liver MODERATORS: Kris V. Kowdley, MD, FACG Paul Y. Kwo, MD, FACG 28. Association Between Aspirin Use and Prevalence of Nonalcoholic Fatty Liver Disease: A Cross-Sectional Study From the Third National Health and Nutrition Examination Survey Huafeng Shen, MD, Ghulamullah Shahzad, MD, Mahreema Jawairia, MD, Paul Mustacchia, MD, NUMC, East Meadow, NY 23. Over-The-Scope-Clip and Cap-Assisted Method for the Resection of Submucosal Lesions of the Gastrointestinal Tract: A Multi-Center Study Shabnam Sarker, MD, Marcel Sandmann, MD, Martin Faendrich, MD, Kondal Kyanam Kabir Baig, MD, Klaus Monkemuller, MD, PhD, Gastroenterology, University of Alabama, Birmingham, AL, Klinikum Dortmund, Dortmund, Germany 29. Serum Ceruloplasmin, Ferritin, and Their Ratio Are Significantly Associated with Nonalcoholic Steatohepatitis in Patients with NAFLD Danny Issa, MD, Rocio Lopez, MS, Ariel E. Feldstein, MD, Mohamed Yaseen Alsabbagh, MD, Naim Alkhouri, MD, Cleveland Clinic, Cleveland, OH 24. Is Cold Biopsy the Best Method for Diminutive Colonic Polyp Removal? A Systematic Review and Meta-analysis Dany Raad, MD, Priyam Tripathi, MD, MPH, Gregory Cooper, MD, FACG, Yngve Falck-Ytter, MD, Case Western Reserve University/ University Hospitals Case Medical Center/VA Medical Center, Cleveland, OH 30. Mean Platelet Volume, Red Cell Distribution Width to Platelet Count Index, Globulin Platelet Index and 12 Other Simple Non-invasive Fibrosis Scores: How Much Do Routine Blood Tests Tell About Liver Fibrosis?  2014 ACG Governors Award for Excellence in Clinical Research Ragesh B. Thandassery, MD, DM, Anil John, MD, DM, MRCP, Madiha Soofi, MD, Syed A. Mohiuddin, MBBS, Mohammed E. Elbadri, MD, Saad Al Kaabi, MD, Division of Gastroenterology, Department of Medicine, Hamad Medical Corporation, Doha, Qatar, Department of Laboratory Medicine and Pathology, Hamad Medical Corporation, Doha, Qatar 25. Withdrawal Times, Adenoma Detection Rates, and Risk of Interval Colorectal Cancer  2014 ACG Colorectal Cancer Prevention Award Aasma Shaukat, MD, MPH, FACG, Thomas Rector, PhD, Timothy R. Church, PhD, Frank Lederle, MD, Adam S. Kim, MD, Jeffrey Rank, MD, John I. Allen, MD, Minneapolis VA Medical Center, Minneapolis, MN, University of Minnesota, Minneapolis, MN, Minnesota Gastroenterology, PA, Minneapolis, MN 31. Idiosyncratic Drug-Induced Liver Injury (DILI) in the United States: A Report of 1,257 Prospectively Enrolled Patients  2014 ACG Governors Award for Excellence in Clinical Research Naga P. Chalasani, MD, FACG, Herbert Bonkovsky, MD, FACG, Robert Fontana, MD, William Lee, MD, FACG, Andrew Stolz, MD, Jay Talwalkar, MD, FACG, Rajender Reddy, MD, FACG, Paul Watkins, MD, Victor Navarro, MD, Huiman Barnhart, PhD, Jiezhun Gu, PhD, Jose Serrano, MD, Indiana University School of Medicine, Indianapolis, IN, Carolinas Health Care System, Charlotte, NC, University of Michigan, Ann Arbor, MI, UT-Southwestern, Dallas, TX, University of Southern California, Los Angeles, CA, Mayo Clinic, Rochester, MN, University of Pennsylvania, Philadelphia, PA, University of North Carolina, Chapel Hill, NC, Einstein Medical Center, Philadelphia, PA, Duke Clinical Research Institute, Durham, NC, NIDDK, Bethesda, MD 26. A Phase-3 Placebo-Controlled Trial of Celecoxib in Pediatric Subjects With Familial Adenomatous Polyposis Carol A. Burke, MD, FACG, Patrick M. Lynch, MD, Robin K. Phillips, MD, Manuela F. Berger, MD, Chunming Li, PhD, Dinu Iorga, MD, Cleveland Clinic, Cleveland, OH, MD Anderson Cancer Center, Houston, TX, St. Marks Hospital, Middlesex, London, United Kingdom, Pfizer, Inc., New York, NY combined abstracts 27A. Statewide, Population-Based Lynch Syndrome (LS) Screening by Microsatellite Instability (MSI) in Colorectal Cancer (CRC) Patients Aged ≤50 Years: Frequency, Determinants of Testing, and Result Analysis  2014 ACG Governors Award for Excellence in Clinical Research Jordan J. Karlitz, MD, Mei-chin Hsieh, MSPH, Yong Liu, BS, Christine Blanton, MD, Beth Schmidt, MSPH, Xiao-Cheng Wu, MD, MPH, Vivien W. Chen, PhD, MPH, Medicine, Tulane UniverFor more information on ACG 2014 and to register, visit www.acgmeetings.gi.org. 30 Annual Scientific Meeting Agenda – Tuesday, October 21 32. Health Related Quality of Life (HRQL) and Health Utilities (HU) of Patients With Chronic Hepatitis C (CH-C) Treated With an Interferon (IFN)-Free Regimen Containing Ledipasvir (LDV) and Sofosbuvir (SOF) Zobair Younossi, MD, MPH, FACG, Maria Stepanova, PhD, Patrick Marcellin, MD, PhD, Nezam Afdhal, MD, Kris V. Kowdley, MD, FACG, Stefan Zeuzem, MD, Linda Henry, PhD, Sharon Hunt, MBA, Center for Liver Diseases, Department of Medicine, Inova Fairfax Hospital, Falls Church, VA; CLDQ LLC, Washington, DC, Viral Hepatitis Research Unit in Hospital Beaujon, Clichy, France, Beth Israel Deaconess Medical Center, Boston, MA, Digestive Diseases Institute, Digestive Diseases Institute, Virginia Mason Clinic, Seattle, WA, Department of Medicine, J.W. Goethe University Hospital, Frankfurt, Germany, Betty and Guy Beatty Center for Integrated Research, Inova Health System, Falls Church, VA 10:00 am  –  4:30 pm Exhibit Hall Opens 10:00 am  –  4:30 pm Hands-on Workshop Center 33. Management of Hemoglobin Decrease in Patients Treated With ABT-450/Ritonavir/Ombitasvir and Dasabuvir With or Without Ribavirin in HCV Genotype 1-infected Patients Vinod Rustgi, MD, FACG, David Bernstein, MD, FACG, Thomas Sepe, MD, FACG, William King, MD, Moises Diago, MD, Pietro Andreone, MD, Daniel Forton, PhD, Hendrik Reesink, MD, Peter Ferenci, MD, Yiran Hu, MS, Jeffrey Enejosa, MD, Daniel Cohen, MD, Yan Luo, MD, PhD, Marcos Pedrosa, MD, PhD, John Vierling, MD, Metropolitan Research, Fairfax, VA, North Shore University Hospital (BRANY), Manhasset, NY, University Gastroenterology, Providence, RI, Trial Management Associates, LLC, Wilmington, NC, Hospital Quirón de Valencia, Unidad de Hepatología, Servicio de Aparato Digestivo, Valencia, Spain, Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy, St. George’s, University of London, London, United Kingdom, Academisch Medisch Centrum, Universiteit van Amsterdam, Gastroenterology & Hepatology, Amsterdam, Netherlands, Department of Internal Medicine 3, Medical University of Vienna, Vienna, Austria, AbbVie Inc., North Chicago, IL, Advanced Liver Therapies, Baylor St. Luke’s Medical Center, Houston, TX moderator: Douglas K. Rex, MD, MACG (Exhibit Halls DE) 10:30 am  –  11:30 am Break – Visit Exhibits (Exhibit Halls DE) 10:30 am  –  11:30 am Exhibitor theater (Exhibit Halls DE) 11:30 am  –  12:45 pm Simultaneous Symposia 3 simultaneous symposia 3a:Quality Here and Now in Colonoscopy: Quality Indicators in Colonoscopy and How to Improve Them in Practice Aasma Shaukat, MD, MPH, FACG Define current quality indicators and discuss technology and techniques to improve them in practice. Detection and Resection of Serrated Polyps Douglas K. Rex, MD, MACG Determine the classification, pathology variation and methods to improve detection and resection of serrated polyps. Controversies in Surveillance Guidelines Dennis J. Ahnen, MD Analyze surveillance guidelines for serrated polyps and other grey areas. simultaneous symposia 3b:Reading Between the Lines: The Refractory Esophageal Patient – What the Guidelines Do Not Address moderator: Evan S. Dellon, MD, MPH 34. Sex, Age and Race Are Associated With Increased Risk of Exposure to Hepatitis E in the U.S. Tyler B. Fleming, MD, Alla Y. Grigorian, MD, PhD, Bilal Aslam, MS, IV, Philip Westgate, PhD, Houssam E. Mardini, MD, MPH, University of Kentucky College of Medicine, Lexington, KY, University of Kentucky College of Public Health, Lexington, KY Achalasia: New Treatment Paradigms Steven R. DeMeester, MD, FACG Describe new treatments, including POEM, as well as patient selection for surgical therapy and management of post-surgical complications. EoE: When Steroids Fail Evan S. Dellon, MD, MPH 35. The Impact of Hyponatremia on the Outcomes of Wait-Listed and Transplanted Patients With Liver Cirrhosis Mohammed Eyad Yaseen Alsabbagh, MD, Bayan Alsuleiman, MD, Naim Alkhouri, MD, Cleveland Clinic, Cleveland, OH Discuss the reasons and treatment approaches for steroid-refractory EoE patients, including dietary elimination and dilation. Refractory GERD: What Are the Options in 2014? Ronnie Fass, MD, FACG 36. Reserved for Late Breaking Abstract Describe current treatment options for PPI-refractory GERD, optimal selection of patients for surgery and post-op complications/recurrences. J. Edward Berk Distinguished Lecture (Terrace Ballroom 3) GI and Endoscopic Training for the Future Gastroenterologist Richard A. Kozarek, MD, FACG Identify the fundamentals of GI and endoscopic training for tomorrow’s GI. Introduced by: Harry E. Sarles, Jr., MD, FACG ACG President 12:45 pm  –  2:15 pm Lunch Break (Exhibit Halls DE) 12:45 pm  –  2:15 pm ANNUAL MEETING 10:00 am  –  10:30 am (Exhibit Halls DE) Poster Session (Exhibit Halls DE) 12:45 pm  –  1:15 pm Exhibitor theater (Exhibit Halls DE) See page 4 for more information. 1:45 pm  –  2:15 pm Exhibitor theater (Exhibit Halls DE) 31 For more information on ACG 2014 and to register, visit www.acgmeetings.gi.org. Annual Scientific Meeting Agenda – Tuesday, October 21 2:15 pm  –  3:45 pm Simultaneous Plenary Sessions 42. Improvement in Symptoms and QOL Is Sustained With Minimal Side Effects 4 Years After Magnetic Sphincter Augmentation (LINX) for GERD Philip O. Katz, MD, FACG, Kenneth R. DeVault, MD, FACG, Steven A. Edmundowicz, MD, Steven C. Schlack-Haerer, MD, Robert A. Ganz, MD, Einstein Medical Center, Philadelphia, PA, Mayo Clinic Florida, Jacksonville, FL, Washington University School of Medicine, St. Louis, MO, Gundersen Health System, La Crosse, Wisconsin, Minnesota Gastroenterology, Minneapolis, MN Plenary Session 1: Esophagus MODERATORS: Nicholas J. Shaheen, MD, MPH, FACG Marcelo F. Vela, MD, FACG 37. Efficacy of Topical Corticosteroids in the Treatment of Eosinophilic Esophagitis: A Meta-Analysis and Systematic Review of Placebo Controlled Randomized Clinical Trials Ashutosh Gupta, MD, Venkatesh Ravi, MD, Arvind R. Murali, MD, Bashar M. Attar, MD, PhD, FACG, Pramoda Koduru, MD, John H. Stroger Hospital of Cook County, Chicago, IL 43. Reserved for Late Breaking Abstract 44. Reserved for Late Breaking Abstract 38. Site Volume Is Inversely Associated With Recurrence Rate After Successful Radiofrequency Ablation (RFA): An Analysis of the U.S. RFA Registry Cary C. Cotton, BA, W. Asher Wolf, MD, MPH, Srinadh Komanduri, MD, MS, Charles J. Lightdale, MD, MACG, Anthony Infantolino, MD, FACG, Herbert C. Wolfsen, MD, FACG, Nicholas J. Shaheen, MD, MPH, FACG, University of North Carolina, Center for Esophageal Diseases and Swallowing, Division of Gastroenterology and Hepatology, Chapel Hill, NC, Northwestern University Feinberg School of Medicine, Chicago, IL, Columbia University Department of Medicine, New York, NY, Jefferson Medical College, Philadelphia, PA, Mayo Clinic Florida, Jacksonville, FL 39. DNA Methylation Changes in Barrett’s Epithelium and Adjacent Normal Mucosa Tamas A. Gonda, MD, Samuel Stevens, BA, Clare LaFave, PhD, Charles J. Lightdale, MD, MACG, Benjamin Tycko, MD, PhD, Gastroenterology, Columbia University Medical Center, New York, NY Plenary Session 2: Pancreatic / Biliary MODERATORS: Linda S. Lee, MD Scott M. Tenner, MD, MPH, JD, FACG 46. Rapid Point-of-Care Measurement of Cyst Fluid Glucose Is Feasible and Accurate in Predicting Mucinous Pancreatic Cysts Thomas Zikos, MD, Kimberly Pham, MS, Ann Chen, MD, Subhas Banerjee, MD, Shai Friedland, MD, MS, Monica Dua, MD, Jeffrey Norton, MD, George Poultsides, MD, MS, Brenda Visser, MD, Walter Park, MD, MS, Medicine/Gastroenterology, Stanford University, Stanford, CA 47. RNA Sequencing of Cystic Lesions of the Pancreas Sarah Rodriguez, MD, Terry Morgan, PhD, Brintha K. Enestvedt, MD, Carl Pelz, Gene Bakis, MD, Soren Impey, PhD, Gastroenterology, The Oregon Clinic-West, Portland, OR, Oregon Health and Science University, Portland, OR 40. Endoscopic Radiofrequency Energy Delivery to the Lower Esophageal Sphincter for Gastroesophageal Reflux Disease: A Systematic Review and Meta-Analysis  2014 ACG Fellow Award Seth Lipka, MD, Ambuj Kumar, MD, MPH, Joel E. Richter, MD, MACG, Digestive Diseases and Nutrition, University of South Florida, Morsani College of Medicine, Tampa, FL, Division of Evidence Based Medicine and Outcomes Research, University of South Florida, Morsani College of Medicine, Tampa, FL, Department of Digestive Diseases and Nutrition, University of South FL, Morsani College of Medicine, Joy McCann Culverhouse Center for Swallowing Disorders, Tampa, FL 48. Risk Factors for Malignant Progression of Intraductal Papillary Mucinous Neoplasms (IPMN): An International Registry Cohort Maria Moris Felgueroso, MD, Michael B. Wallace, MD, FACG, Massimo Raimondo, MD, FACG, Timothy A. Woodward, MD, Verna J. Skinner, MD, Paolo G. Arcidiacono, MD, Cinzia Boemo, MD, Maria C. Petrone, MD, Claudio De Angelis, MD, Selene F. Manfre, MD, Pietro Fusaroli, MD, Michele Lewis, MD, Mayo Clinic Jacksonville, Jacksonville, FL, San Raffaele Scientific Institute, Milan, Italy, University of Turin, Turin, Italy, Ospedale di Castel San Pietro Terme, Bologna, Italy 41. Transoral Fundoplication Provides Better GERD Symptom Control Than PPIs in Patients With Troublesome Regurgitation: A Multicenter Sham-Controlled Randomized Clinical Trial Peter J. Kahrilas, MD, FACG, John Hunter, MD, Reginald Bell, MD, Erik Wilson, MD, Karim Trad, MD, James Dolan, MD, Kyle Perry, MD, Brant Oelschlager, MD, Nathaniel Soper, MD, Miguel Burch, MD, W. Scott Melvin, MD, Kevin Reavis, MD, Daniel Turgeon, MD, Eric Hungness, MD, Brian Diggs, PhD, Brad Snyder, MD, Medicine, Northwestern University, Chicago, IL, Oregon Health & Science University, Portland, OR, SurgOne Foregut Institute, Englewood, CO, University of Texas Health & Science Center, Houston, TX, The George Washington University of Medicine and Health Sciences, Washington, DC, Reston Surgical Associates, Reston, VA, The Ohio State University, Columbus, OH, University of Washington, Seattle, WA, Cedars-Sinai Medical Center, Los Angeles, CA, Oregon Clinic, Portland, OR For more information on ACG 2014 and to register, visit www.acgmeetings.gi.org. 45. Reserved for Late Breaking Abstract 49. Morbid Obesity (MO) Is Associated With Increased Healthcare Utilization and Is an Independent Predictor of Mortality of Acute Pancreatitis (AP) Somashekar G. Krishna, MD, MPH, Samer El-Dika, MD, Alice Hinton, PhD, Jeffrey R. Groce, MD, Hisham Hussan, MD, Cheng Zhang, MD, PhD, Peter P. Stanich, MD, Na Li, MD, Darwin L. Conwell, MD, MS, Department of Gastroenterology, Hepatology and Nutrition, The Ohio State University Medical Center, Columbus, OH 32 Annual Scientific Meeting Agenda – Tuesday, October 21 50. Acute Pancreatitis (AP) in Post-Bariatric Surgery (BRS) Status: Analysis of National Trends, Complications and Outcomes from 2007 to 2011  2014 ACG Obesity Award Somashekar G. Krishna, MD, MPH, Jennifer Behzadi, MD, Alice Hinton, PhD, Samer El-Dika, MD, Jeffrey R. Groce, MD, Hisham Hussan, MD, Darwin L. Conwell, MD, MS, Department of Gastroenterology, Hepatology and Nutrition, The Ohio State University Medical Center, Columbus, OH 5:00 pm  –  6:15 pm Simultaneous Symposia 4 simultaneous symposia 4a:Obesity: The Hunger Games moderator: Steven A. Edmundowicz, MD Which Surgery Will Keep Your BMI in Check? Alfons Pomp, MD Compare the different surgical options in the management of obesity. Post-operative Complications: Metabolic and Nutritional John K. DiBaise, MD, FACG 51. Prevalence of Exocrine and Endocrine Pancreatic Insufficiency After Sentinel Acute Pancreatitis (AP) Kishore Vipperla, MD, Georgios Papachristou, MD, Adam Slivka, MD, PhD, David Whitcomb, MD, PhD, Dhiraj Yadav, MD, MPH, University of Pittsburgh Medical Center, Pittsburgh, PA Identify and manage the potential metabolic complications post-bariatric surgery. Post-operative Complications: Endoscopic Management Steven A. Edmundowicz, MD 52. Reserved for Late Breaking Abstract Define how to endoscopically manage post-bariatric surgical complications. 53. Reserved for Late Breaking Abstract simultaneous symposia 4b:Pearls and Pitfalls of Routine IBD Management: Case Studies 54. Reserved for Late Breaking Abstract 3:45 pm  –  4:30 pm Break – Visit Exhibits moderator: Uma Mahadevan, MD, FACG (Exhibit Halls DE) The Newly Diagnosed IBD Patient Edward V. Loftus, Jr., MD, FACG 4:30 pm  –  5:00 pm Emily Couric Memorial Lecture (Terrace Ballroom 3) Apply appropriate initial therapy for newly diagnosed IBD patients. Cancer in IBD: The Colon and Beyond Stephen B. Hanauer, MD, FACG Describe the role of surveillance techniques to prevent colon cancer in IBD, and identify the risks of medication-related malignancies in IBD. The Medically Refractory IBD Patient Uma Mahadevan, MD, FACG Apply a comprehensive approach to the patient with refractory symptoms. The Post-operative Patient Miguel D. Regueiro, MD, FACG See page 4 for more information. Sponsored by the ACG, the Virginia Gastroenterological Society and the Old Dominion Society of Gastroenterology Nurses and Associates Apply a therapy for the prevention of recurrence. 6:15 pm Introduced by: Harry E. Sarles, Jr., MD, FACG ACG President ADJOURN ANNUAL MEETING 33 For more information on ACG 2014 and to register, visit www.acgmeetings.gi.org. Annual Scientific Meeting Agenda – Wednesday, October 22 Wednesday, October 22, 2014 breakfast p: Beyond the Burn: Controversies in Barrett's Esophagus 6:45 am – 12:15 pm 6:00 am  –  12:15 pm Registration (Broad Street Atrium) Moderator: Nicholas J. Shaheen, MD, MPH, FACG Difficult Ablation: When to Step on the Pedal and When to Refer Kenneth K. Wang, MD, FACG Discuss cases that present difficulty for ablation such as nodularity, long segment BE, large hiatal hernias and esophageal varices, and determine when they can be safely performed and when a referral is needed. 6:45 am  –  8:15 am OPTIONAL Breakfast Sessions Cost is $60 per person/per session. Separate registration required. A USB containing all ACG 2014 Breakfast Sessions submissions will be provided to attendees registered for any Breakfast Session. See page 124 for registration information. breakfast n: Common Liver Outpatient Consults Afterburn: Surveillance After Ablation and Management of Recurrence Nicholas J. Shaheen, MD, MPH, FACG Moderator: Santiago J. Munoz, MD, FACG The Patient With a Solid Liver Mass K. Rajender Reddy, MD, FACG Explain post-ablation surveillance protocols and the strategy for treating BE recurrence after ablation. Distinguish between benign and malignant liver masses on imaging, and develop strategies to screen for hepatoma in patients with advanced fibrosis. Esophagectomy in 2014: What Is the Role? Steven R. DeMeester, MD, FACG Describe the circumstance in which esophagectomy for BE is still indicated, and differences between the U.S. and British guidelines. The Abnormal Liver Panel Santiago J. Munoz, MD, FACG Evaluate abnormal liver tests and identify the presence or absence of advanced liver disease. breakfast q: Thinking Outside the Bowel: Common Complications of IBD and IBD Therapy The Hepatitis B Infected Patient Joseph K. Lim, MD, FACG Moderator: Jason M. Swoger, MD, MPH Interpret hepatitis B serologies to determine whether to follow or treat the infected patient. breakfast o: Practical Skin Jason M. Swoger, MD, MPH Identify common skin manifestations of IBD and complications from therapy. Colonoscopy Moderator: Joseph C. Anderson, MD Arthralgias Christina Y. Ha, MD What’s New in Colonoscopy Prep Brooks D. Cash, MD, FACG Discuss recent data regarding various prep regimens, qualities, and adjunctive measures to achieve an optimal bowel prep. Differentiate the causes and identify treatment of joint pain in the patient with IBD. Abnormal Liver Function Tests Paul Martin, MD, FACG The Incomplete Colonoscopy: What Next? Jonathan A. Leighton, MD, FACG Outline common liver complications of IBD and IBD therapy. Explain the options for patients who have an incomplete colonoscopy. Approach to the Difficult Polypectomy Charles J. Kahi, MD, FACG Identify techniques for successful and complete polyp resection. For more information on ACG 2014 and to register, visit www.acgmeetings.gi.org. 34 Annual Scientific Meeting Agenda – Wednesday, October 22 6:00 am  –  12:15 pm Registration (Broad Street Atrium) 8:30 am  –  12:15 pm Scientific Meeting 8:30 am  –  10:15 am Simultaneous Plenary Sessions 61. Association of Mean Vitamin D Level With Clinical Status in Inflammatory Bowel Disease: A 5 Year Prospective Study  2014 ACG Fellow Award Toufic A. Kabbani, MD, MPH, Claudia Ramos Rivers, MD, Jason Swoger, MD, MPH, Miguel D. Regueiro, MD, FACG, Arthur M. Barrie, MD, PhD, Marc Schwartz, MD, Jana G. Hashash, MD, Leonard Baidoo, MD, FACG, Michael A. Dunn, MD, David G. Binion, MD, University of Pittsburgh Medical Center, Pittsburgh, PA Plenary Session 1: IBD / Small Intestine / Unclassified MODERATORS: Francis A. Farraye, MD, MSc, FACG Jonathan A. Leighton MD, FACG 62. Health Outcomes of Ulcerative Colitis (UC) and Crohn’s Disease (CD) Patients Hospitalized With Human Cytomegalovirus (CMV) Disease Cheng Zhang, MD, Edward J. Levine, MD, Somashekar G. Krishna, MD, Alice Hinton, PhD, Darwin L. Conwell, MD, Razvan Arsenescu, MD, Inflammatory Bowel Disease Program, Division of Gastroenterology, Hepatology, & Nutrition, The Ohio State University, Columbus, OH; Division of Biostatics, College of Public Health, The Ohio State University, Columbus, OH 55. The Clinical Characteristics of HLA Genotype DQ2.2 in a U.S. Adult Celiac Disease Population  2014 ACG Fellow Award Richard Wu, MD, MPH, Stephanie Moleski, MD, C. Andrew Kistler, MD, PharmD, Beth Colombe, PhD, Anthony DiMarino, MD, Thomas Jefferson University Hospital, Philadelphia, PA 56. Impact of Small Bowel Imaging on the Histological Patterns of Small Bowel Tumors: Analysis With SEER Database  2014 ACG Lawlor Resident Award Felix H. Lui, MD, Richard E. Shaw, PhD, Lauren B. Gerson, MD, FACG, Internal Medicine, California Pacific Medical Center, San Francisco, CA; Division of Clinical Informatics, California Pacific Medical Center, San Francisco, CA; Division of Gastroenterology, California Pacific Medical Center, San Francisco, CA 63. The Risk of a Second Non-Melanoma Skin Cancer With Thiopurine and Anti-TNF Use in Inflammatory Bowel Disease Frank I. Scott, MD, MSCE, Ronac Mamtani, MD, MSCE, Colleen Brensinger, MS, Kevin Haynes, PharmD, MSCE, Zelma C. Chiesa-Fuxench, MD, Jie Zhang, PhD, Lang Chen, MD, PhD, Fenglong Xie, MS, David J. Margolis, MD, PhD, Jeffrey R. Curtis, MD, MS, MPH, James D. Lewis, MD, MSCE, Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, Department of Epidemiology, University of Alabama at Birmingham School of Public Health, Birmingham, AL, Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, Department of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, Division of Gastroenterology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelph, PA 57. Small Bowel Cancer in the U.K. Lolita Chan, BSc, MBChB, MCRP, Gareth Evans, MBBS, MRCP, MD, FRCP, Central Manchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom 58. Mode of Childbirth and Long-term Outcomes in Women With Inflammatory Bowel Diseases  2014 ACG Governors Award for Excellence in Clinical Research Ashwin N. Ananthakrishnan, MD, MPH, Andrew Cagan, BS, Vivian Gainer, MS, Tianxi Cai, PhD, Stanley Shaw, MD, PhD, Susanne Churchill, PhD, Elizabeth Karlsin, MD, MPH, Shawn Murphy, MD, PhD, Isaac Kohane, MD, PhD, Katherine Liao, MD, MPH, Gastrointestinal Unit, Massachusetts General Hospital, Boston, MA; Harvard School of Public Health, Boston, MA, Brigham and Women’s Hospital, Boston, MA, Partners Healthcare, Boston, MA Plenary Session 2: Stomach / Colon MODERATORS: Joseph C. Anderson, MD Francisco C. Ramirez, MD, FACG 59. Updated Incidence and Prevalence of Crohn’s Disease and Ulcerative Colitis in Olmsted County, Minnesota (between 1970 and 2010)  2014 ACG IBD Research Award Raina Shivashankar, MD, William J. Tremaine, MD, FACG, Scott W. Harmsen, MS, Alan Zinsmeister, PhD, Edward V. Loftus, MD, FACG, Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN 64. Risks of Thromboembolism Versus Recurrent GI Hemorrhage After Interruption of Anticoagulation in Admitted Patients With GI Bleeding (GIB) – A Prospective Study Neil Sengupta, MD, Joseph Feuerstein, MD, Vilas R. Patwardhan, MD, Gyanprakash Ketwaroo, MD, Adarsh M. Thaker, MD, Daniel Leffler, MD, Beth Israel Deaconess Medical Center, Boston, MA 35 ANNUAL MEETING 65. Topographical Mapping in a Cohort of Patients With Gastric Intestinal Metaplasia  2014 ACG Fellow Award Manish B. Singla, MD, Steven Armbruster, MD, Nisha Shah, MD, Molly Burman, BSN, Corinne L. Maydonovitch, BS, Patrick E. Young, MD, FACG, Jayde Kurland, MD, FACG, Scott Itzkowitz, DO, FACG, Walter Reed National Military Medical Center, Washington, DC, Gastrointestinal Associates, Lima, OH 60. Impact of Immigration on Phenotype and Severity of Inflammatory Bowel Disease: A Prospective Cohort Study of Hispanics in the United States  2014 ACG IBD Research Award Nirupama Bonthala, MD, Jared Macklin, MD, Syeda Hamadani, MD, Mark Salem, MD, Rachel Demisse, MD, Beverly Chen, MD, Caroline Hwang, MD, Gastroenterolgy and Hepatology, University of Southern California, Los Angeles, CA For more information on ACG 2014 and to register, visit www.acgmeetings.gi.org. Annual Scientific Meeting Agenda – Wednesday, October 22 66. An Assessment of Gastric and Small Bowel Pressure Profiles in Diabetics With Gastroparesis Before and During 28 Days of Treatment With the Motilin Receptor Agonist Camicinal (GSK962040) Kenneth Barshop, MD, George Dukes, MD, Matthew Barton, MD, Jack Semler, MD, Braden Kuo, MD, University of Chicago Pritzker School of Medicine, Chicago, IL, Massachusetts General Hospital, Boston, MA, GlaxoSmithKline, Raleigh, NC 10:15 am  –  10:45 am (Terrace Ballroom 3) Idiosyncratic Drug-Induced Liver Injury: What Have We Learned in the Last Decade? Naga P. Chalasani, MD, FACG Assess recent developments in the diagnosis and management of DILI. Introduced by: Harry E. Sarles, Jr., MD, FACG ACG President 67. Gastric Electric Stimulation: A Prospective Analysis of 151 Patients at a Single Center Jason Heckert, BS, Sean Harbison, MD, Henry P. Parkman, MD, FACG, Temple University, Philadelphia, PA See page 4 for more information. 68. Colorectal Cancer Patients Have Higher Rates of Advanced Features in Their Diminutive Adenomas Compared to Patients Undergoing Average-Risk Screening  2014 ACG Colorectal Cancer Prevention Award Amoah Yeboah-Korang, MD, MPH, MSc, Philip Vutien, MD, Kateri Evans, MS, Michael Greenspan, MD, Sohrab Mobarhan, MD, Shriram Jakate, MD, Joshua Melson, MD, MPH, Rush University Medical Center, Chicago, IL 10:45 am  –  11:00 am Break 11:00 am  –  12:15 pm Simultaneous Symposia 5 simultaneous symposia 5a:The Inpatient Hepatology Consult moderator: Mark W. Russo, MD, MPH, FACG Fluid, Distention, Infection, Oh My: Approach to the Patient With Ascites Mark W. Russo, MD, MPH, FACG Treat patients with massive ascites and spontaneous bacterial peritonitis. 69. Insertion Water Exchange Minimizes Endoscopist Multitasking During Withdrawal Inspection: A Plausible Explanation for Enhanced Polyp Detection in the Right Colon Andrew Yen, MD, FACG, Victoria Y. Yung, MD, Joseph W. Leung, MD, MACG, Surinder Mann, MD, FACG, Machelle D. Wilson, PhD, Felix W. Leung, MD, FACG, Sacramento VA Medical Center, VANCHCS, Mather, CA, University of California, Davis Medical Center, Sacramento, CA, Sepulveda Ambulatory Care Center, VAGLAHS, North Hills, CA Water, Water Everywhere: Approach to the Cirrhotic Patient With Acute Kidney Injury Jasmohan S. Bajaj, MD, FACG Evaluate the cirrhotic patient with acute kidney injury, including hepatorenal syndrome, acute kidney injury and hyponatremia. 70. Comparing Diagnostic Tests in Dyssynergic DefecationConstipation Danse Bi, MD, Sandra Sostrich, MD, Mojtaba Olyaee, MD, Elena Sidorenko, MD, Tuba Esfandyari, MD, University of Kansas Medical Center, Kansas City, KS A Rational Guide to the Use of TIPS Atif Zaman, MD, FACG Discuss appropriate indications for TIPS referrals and manage post-TIPS complications. 71. Clostridium difficile Associated Risk of Death Score (CARDS): A Novel Risk Score to Predict Mortality Among Hospitalized Patients With Clostridium difficile Infection  2014 ACG Fellow Award Zain Kassam, MD, MPH, Camila Cribb Fabersunne, MD, MPH Candidate, Mark B. Smith, MD, PhD Candidate, Gilaad G. Kaplan, MD, MPH, Geoffrey C. Nguyen, MD, PhD, Ashwin N. Ananthakrishnan, MBBS, MPH, Massachusetts Institute of Technology, Cambridge, MA, Harvard Medical School, Boston, MA, University of Calgary, Calgary, Alberta, Canada, University of Toronto, Toronto, Ontario, Canada, Massachusetts General Hospital, Boston, MA simultaneous symposia 5b:The Human Microbiome moderator: Eamonn M. M. Quigley, MD, FACG Human Intestinal Microbiome: What the Practicing Gastroenterologist Should Know Eamonn M. M. Quigley, MD, FACG Identify how the microbiome functions and interacts within the GI tract. What Is the Evidence that the Intestinal Microbiome Has a Role in Gastrointestinal Diseases? Lawrence J. Brandt, MD, MACG 72. Fresh, Frozen, or Lyophilized Fecal Microbiota Transplantation (FMT) for Multiple Recurrent C. difficile Infection (CDI) Zhi-Dong Jiang, PhD, Nadim J. Ajami, PhD, Todd Lasco, PhD, Joe Petrosino, PhD, Fredric Hochman, MD, Victor Ankoma-Sey, MD, Matthew Wong, PhD, Ashley Alexander, MS, Shi Ke, MS, Herbert L. DuPont, MD, University of Texas SPH, Houston, TX, Baylor College of Medicine, Houston, TX, Baylor St. Luke’s Medical Center, Houston, TX Define the role of the human microbiome in relation to GI disorders. Targeting the Intestine Microbiota in the Treatment of Gastrointestinal Diseases Yehuda Ringel, MD, FACG Assess the role of the human microbiome in the treatment of GI diseases. 12:15 pm For more information on ACG 2014 and to register, visit www.acgmeetings.gi.org. David Y. Graham Lecture 36 ANNUAL SCIENTIFIC MEETING ADJOURNS